Measurement and correlation on solubility of acetaminophen in aqueous solutions of 1-alkyl-3-methyl imidazolium ionic liquid
کد مقاله : 1187-PHYSCHEM20
Abbas Mehrdad *
Tabriz University
چکیده مقاله:
Aqueous solubility of acetaminophen (ACP) in the presence of 1-octyl-3-methyl imidazolium bromide ionic liquid, as co-solvent was investigated at different temperatures and mass fraction of ionic liquid. The obtained results reveal that the solubility of acetaminophen was increased by increasing temperature and concentration of ionic liquid. Solubility of ACP was significantly increased when mass fraction of 1-octyl-3-methyl imidazolium bromide reaches to more than 0.05. The possible reasons behind enhanced solubility of ACP in aqueous solution of ionic liquid are hydrophobic interaction and the formed micelles by cations of ionic liquid. The experimental solubility of acetaminophen was correlated with the modified Wilson and the electrolyte-NRTL models as activity coefficient model.
کلیدواژه ها:
Solubility, Acetaminophen, Ionic liquid, Wilson model, NRTL model
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